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 Berberine - The Metformin of the  Natural World!

Berberine is a component that has proved itself when used as an anti-biotic. It has been used against:

  • salmonella

  • urinary tract infections 

  • gonorrhea

  • cholera, and many other infections.

It is found as the active ingredient in many herbs, and is well known as an immune system stimulant. 

After much researched and study, it was found to be as effective and even safer than Metformin, the well known oral medication for type 2 diabetics.

Studies tested on humans when it was used found that there was a significant drop in fasting blood sugars, post-prandial (after meal glucose levels), A1c and even cholesterol.

How does it work? - Enzymes, Incretins, and Glucagon...

...all play a roll when Berberine is used as a blood sugar regulator. While this information is some what technical it is important - I'll keep it simple.

The first enzyme I'll discuss is called AMPK (Activated Protein Kinease),which among other functions regulate the cellular intake of insulin. It does so by...

...increasing insulin receptors in the body. This of course increases insulin activity.  Another enzyme is PTP1b (protein tyrosine Phosphatase 1B) This enzyme has an opposite...

...effect of AMPK. It inhibits the insulin receptors, prohibiting them from functioning at their fullest potential. Berberine counter acts this, allowing the receptors to do what they are suppose to - remove glucose from the blood and into the cells.


Incretins are hormones that increases the amount of insulin in the body. These hormones are secreted by the intestines. Incretins also slow down the rate of nutrients entering into the blood stream, thus regulating how fast glucose enters the blood.

Huang-lian is a herb that contains the active ingredient Berberine. Huang-Lian has been used in China for thousands of years for type 2  diabetes (I don't know what is was called then). 

It was originally used to treat diarrhea. It was recognized that when given to those with type 2 diabetes, there was a blood sugar lowering effect. 

There are many publications and studies that this compound can effectively lower and regulate blood sugars.Some of these studies also show that it is just as effective as the drug Metformin (Glucophage) and may also boost it's effect.

So if you are taking the medication Metformin and are looking for a alternative OR a supplement, this may be the the choice. A natural one.

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The statements above have not been evaluated by the Food and Drug Administration. The above products are not intended to diagnose, treat, cure, or prevent any disease.

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